Lymphoma

Study: A Phase II Clinical Trial Evaluating Ibrutinib Maintenance Following Intensive Induction for Patients with Previously Untreated Mantle Cell Lymphoma (MCL)
Clinical Trial #: NU 14H06
Principal Investigator: Valerie Nelson, MD

Learn more at Clinicaltrials.gov^*

Study: A Single Arm Phase II Study Evaluating the Efficacy and Safety of Durvalumab (MEDI4736) in Combination with Tremelimumab in Patients with Metastatic HER2 Negative Breast Cancer: TNBC Expansion Cohort
Clinical Trial #: NU 15B01
Principal Investigator: Valerie Nelson, MD

Learn more at Clinicaltrials.gov^*

Study: A large-scale multicenter phase II study evaluating the protective effect of a tissue selective estrogen complex (TSEC) in women with newly diagnosed ductal carcinoma in situ.
Clinical Trial #: NU 15B06
Principal Investigator: Valerie Nelson, MD

Learn more at Clinicaltrials.gov^*

Study: A Phase II Single Arm Study of Palbociclib in Patients with Metastatic HER2-positive Breast Cancer with Brain Metastasis
Clinical Trial #: NU 15B08
Principal Investigator: Valerie Nelson, MD

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Study: A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy Vs. Capecitabine in Patients with Residual Triple-Negative Basal-Like Breast Cancer following Neoadjuvant Chemotherapy
Clinical Trial #: ECOG-ACRIN 1131
Principal Investigator: Valerie Nelson, MD

Learn more at Clinicaltrials.gov^*

Study: A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer
Clinical Trial #: NRG BR003
Principal Investigator: Valerie Nelson, MD

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Study: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy
Clinical Trial #: NSABP B-51
Principal Investigator: Valerie Nelson, MD

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Study: Phase-III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/neu Negative Breast Cancer. e3 Breast Cancer Study - evaluating everolimus with endocrine therapy
Clinical Trial #: SWOG 1207
Principal Investigator: Valerie Nelson, MD

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Study: A randomized, phase III trial to evaluate the efficacy and safety of MK-3475 (pembrolizumab) as adjuvant therapy for triple-negative breast cancer with >1 cm residual invasive cancer or positive lymph nodes after neoadjuvant chemotherapy
Clinical Trial #: SWOG 1418
Principal Investigator: Valerie Nelson, MD

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Study: A Phase II Study of FOLFOX combined with Nab-Paclitaxel (FOLFOX-A) in Treatment of Metastatic or Advanced Unresectable Gastric, Gastro-Esophageal Junction Adenocarcinoma
Clinical Trial #: BTCRC GI15-015
Principal Investigator: Valerie Nelson, MD

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Study: Parallel Proof Of Concept Phase 2 Study Of Nivolumab And Metformin Combination Treatment In Advanced Non-Small Cell Lung Cancer With And Without Prior Treatment With PD-1/PD-L1 Inhibitors
Clinical Trial #: NU 16L04
Principal Investigator: Valerie Nelson, MD

Learn more at Clinicaltrials.gov^*

Sarcoma

Study: A Phase II Study of Pazopanib with Oral Topotecan in Patients with Metastatic and Non-resectable Soft Tissue and Bone Sarcomas
Clinical Trial #: NU 14S03
Principal Investigator: Valerie Nelson, MD

Learn more at Clinicaltrials.gov^*

Endometrial

Study: Phase II Study of Pembrolizumab in Combination with Carboplatin and Paclitaxel for Advanced or Recurrent Endometrial Adenocarcinoma
Clinical Trial #: BTCRC GYN15-013
Principal Investigator: Valerie Nelson, MD

Learn more at Clinicaltrials.gov^*

Ovarian

Study: An Open Label Phase II Trial of Guadecitabine and Pembrolizumab in Platinum Resistant Recurrent Ovarian Cancer
Clinical Trial #: NU 16G03
Principal Investigator: Valerie Nelson, MD

Learn more at Clinicaltrials.gov^*